mutation

Bioinformatics, Data Science

#note Population Genetics A Concise Guide (18)

This is a note for the book Population Genetics: A Concise Guide (Second Edition). Page 31 Problem 2.9 Graph -ΔNH and ΔuH as function of H for N = 104 and u = 5×10-5. Do the lines intersect where you expect them to? Note: Output: In this situation, 4Nu = 4×104×10-5 = 2, when H > […]

Bioinformatics, Data Science

#note Population Genetics A Concise Guide (17)

This is a note for the book Population Genetics: A Concise Guide (Second Edition). Page 30 Problem 2.8 Graph Equation 2.7 as a function of 4Nu. What value of 4Nu gives a reasonable fit to the average heterozygosity for proteins as described by electrophoretic studies in humans? Note: Equation 2.7: Set t = 4Nu Output: Proteins

Bioinformatics, Data Science

#note Population Genetics A Concise Guide (16)

This is a note for the book Population Genetics: A Concise Guide (Second Edition). Page 30 Problem 2.7 How many different alleles are one mutational step away from an allele at a locus that is 3000 nucleotides in extend? How many are two mutational step away? Note: One nucleotide has one of the three possibilities of

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